PPCX Capsule

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The PPCX Capsule Filter is a validated, double-layered, positively charged PES membrane filter engineered for absolute-rated sterilization and endotoxin removal. Designed for aqueous solutions containing negatively charged biological contaminants, PPCX is ideal for pharmaceutical and bioprocessing applications requiring high flow and high retention.

PPCX capsules offer broad chemical compatibility and deliver > 3-log removal of endotoxins while meeting FDA and USP standards for purity and performance.

Key Features:

• Dual-Layer Positively Charged PES Membrane
• Validated Bacterial Retention – > 7-log removal
• > 3-log Endotoxin Reduction Capability
• High Throughput with Broad Chemical Compatibility
• Presterilized Capsule Options Available

Performance Parameters:

• Max Operating Temp (Water): 110 °F at 30 psid (43 °C at 2.07 bar)
• Forward Pressure Limit: 80 psid at 68 °F
• Reverse Pressure Limit: 50 psid at 68 °F
• Recommended Changeout: 35 psid

Sterilization & Cleaning:

• Autoclave: 250 °F (121 °C), 30 min, 25+ cycles
• Inline Steam: 275 °F (135 °C), 30 min
• Hot Water: 194 °F (90 °C), 30 min, max 3 psid forward
• Compatible with hydrogen peroxide, peracetic acid, and standard cleaning agents

Filtration Area (Nominal):

• 2" – 1.0 ft² (0.10 m²)
• 5" – 2.9 ft² (0.27 m²)
• 10" – 6.1 ft² (0.57 m²)
• 20" – 12.2 ft² (1.14 m²)
• 30" – 18.3 ft² (1.71 m²)
• 40" – 24.4 ft² (2.28 m²)

Construction Materials:

• Filtration Media: Positively Charged Dual-Layer PES
• Capsule Housing: Polypropylene
• Sealing Method: Thermal Bonding

Validated Microbial Retention:

• 0.03 μm: Acholeplasma laidlawii
• 0.10 μm & 0.22 μm: Brevundimonas diminuta
• 0.45 μm: Serratia marcescens

Typical Applications:

• Process Water
• Water for Injection (WFI)
• Biopharmaceutical Solutions
• Sterilizing Filtration
• Endotoxin Removal